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Deltasonamide 2
CAS No. 2088485-34-9
Deltasonamide 2( Deltasonamide2 )
Catalog No. M13258 CAS No. 2088485-34-9
Deltasonamide 2 (Deltasonamide-2) isa novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 385 pM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDeltasonamide 2
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NoteResearch use only, not for human use.
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Brief DescriptionDeltasonamide 2 (Deltasonamide-2) isa novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 385 pM.
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DescriptionDeltasonamide 2 (Deltasonamide-2) isa novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 385 pM; inhibits PDE6δ/KRas interaction in cells with Kd of 64 nM, selectively inhibits growth of KRas mutated and -dependent cells, inhibits the oncogenic KRas-dependent MiaPaCa-2 with IC50 of 750 nM.
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SynonymsDeltasonamide2
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PathwayMAPK/ERK Signaling
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TargetRas
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RecptorRas
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Research Area——
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Indication——
Chemical Information
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CAS Number2088485-34-9
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Formula Weight647.25
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Molecular FormulaC30H39ClN6O4S2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S(C1=CC=C(S(=O)(N(CC2=CC=C(Cl)C=C2)C3CCCC3)=O)C=C1)(N([C@H]4CC[C@H](N)CC4)CC5=NC(NC)=NC=C5)=O
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Chemical NameN1-((1r,4r)-4-aminocyclohexyl)-N4-(4-chlorobenzyl)-N4-cyclopentyl-N1-((2-(methylamino)pyrimidin-4-yl)methyl)benzene-1,4-disulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Martín-Gago P, et al. Angew Chem Int Ed Engl. 2017 Feb 20;56(9):2423-2428.
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