Cart
sales@molnova.com
Deltasonamide 2
CAS No. 2088485-34-9
Deltasonamide 2( Deltasonamide2 )
Catalog No. M13258 CAS No. 2088485-34-9
Deltasonamide 2 (Deltasonamide-2) is?a novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 385 pM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameDeltasonamide 2
-
NoteResearch use only, not for human use.
-
Brief DescriptionDeltasonamide 2 (Deltasonamide-2) is?a novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 385 pM.
-
DescriptionDeltasonamide 2 (Deltasonamide-2) is?a novel small molecule inhibitor of PDE6δ/KRas interaction with Kd of 385 pM; inhibits PDE6δ/KRas interaction in cells with Kd of 64 nM, selectively inhibits growth of KRas mutated and -dependent cells, inhibits the oncogenic KRas-dependent MiaPaCa-2 with IC50 of 750 nM.
-
In Vitro——
-
In Vivo——
-
SynonymsDeltasonamide2
-
PathwayMAPK/ERK Signaling
-
TargetRas
-
RecptorRas
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2088485-34-9
-
Formula Weight647.25
-
Molecular FormulaC30H39ClN6O4S2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=S(C1=CC=C(S(=O)(N(CC2=CC=C(Cl)C=C2)C3CCCC3)=O)C=C1)(N([C@H]4CC[C@H](N)CC4)CC5=NC(NC)=NC=C5)=O
-
Chemical NameN1-((1r,4r)-4-aminocyclohexyl)-N4-(4-chlorobenzyl)-N4-cyclopentyl-N1-((2-(methylamino)pyrimidin-4-yl)methyl)benzene-1,4-disulfonamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Martín-Gago P, et al. Angew Chem Int Ed Engl. 2017 Feb 20;56(9):2423-2428.
molnova catalog
related products
-
pan-Ras inhibitor 31...
pan-Ras inhibitor 3144 (Compound 3144) is a multivalent small-molecule, pan-RAS inhibitor.
-
K-Ras G12C-IN-4
K-Ras G12C-IN-4 is a potent co-valent Inhibitor of KRAS G12C.
-
BI-3406
BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.
